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Across these periods, most of the selected diseases showed increased adoption (Fig

doi: 10.1515/hsz-2016-0202 90 FraternaleA.PaolettiM

The applied rationale of skin and colon wounds (Seiwerth et al., 1997) covers the different healing patterns and dynamics of these organs related to their collagen structures (Seiwerth et al., 1997)

Non-selective c-Met inhibitors include crizotinib (PF-02341066), foretinib (XL-880), cabozantinib (XL-184), glesatinib (MGCD265), BMS-777607, and MK2461, which in addition to c-Met, can inhibit other tyrosine kinases, such as ALK, RON, VEGFR2, KIT, TIE2, PDGFR, VEGFR1, VEGFR3, RET, and FLT-3 [163,164,165], through binding to the ATP binding site on tyrosine kinases