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The homologous cytochrome CYP2A6 of humans in Cyp2a5 mice is expressed in several liver diseases by the induction of toxic chemicals [77], where the levels of mRNA and Cyp2a5, on comparison between knockout NRF-2/ and wild-type mice, proved the increase of NRF-2 and Cyp2a5 in wild-type mice, as well as their interaction by co-immunoprecipitation Cyp controlled by NRF-2 [77]

Supplementation of GLY alone has been investigated in rodent models

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In a recent study, an 8-week vitamin D3 intervention (50,000 IU per week) in children with ADHD not only increased serum levels of this vitamin, but also reported that its use during feedback may elicit more favourable clinical and electrophysiological outcomes [79]