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This oxidative stress plays a central role in disease progression from simple steatosis to more serious conditions such as non-alcoholic steatohepatitis (NASH), fibrosis, and potentially cirrhosis

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Data availability The cryo-EM maps and coordinates for the GluK2 in the non-active state have been deposited in the Electron Microscopy Data Bank (EMDB) under accession numbers EMD-48765 (ATD), EMD-48766 (LBD-TMD), and EMD-48767 (full-length, composite map), and in the PDB under accession codes 9MZQ (ATD), 9MZR (LBD-TMD) and 9MZS (full-length), respectively