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Collectively, 47 phosphopeptides were detected from 24 proteins (Table 1), among which we report for the first time 8 phosphoproteins with a total of 19 phosphopeptides in human CSF

When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects

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