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ROS-induced mitochondrial dysfunction and DNA damage, along with the inhibition of key redox transcription factors such as Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) may contribute to the persistence of symptoms in both ME/CFS and Long COVID (Jarrott et al., 2022)

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The peptide appears to interact with nitric oxide pathways in the central nervous system, potentially influencing neurotransmitter balance and synaptic function

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