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l-Pro, the lipid peroxidation, and ROS level significantly increased

Concordantly, mice deficient in Aldh2 and Adh5 recapitulate some of the hematopoietic phenotypes of IBMFS/AMeD patients 10

The number of animals assigned per condition was selected to account for the variability of the examined phenotypes based on pilot experiment and past experience with the animal models (6 animals per experimental condition)