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However, the large proportion of CFTR expression deriving from other epithelial cell types and our observation of FOXI1 / CFTR decoupling by time course and knockout electrophysiology cautions against the simple model where cystic fibrosis is caused by loss of CFTR function in FOXI1 + ionocytes

AND WHEREAS, the 43rd World Health Assembly in its Fourteenth Plenary meeting held on the 17th May, 1990, reiterated the concerns expressed in the Resolution passed in the 39th World Health Assembly and urged Member States to consider in their tobacco control strategies plans for legislation and other effective measures for protecting their citizens with special attention to risk groups such as pregnant women and children from involuntary exposure to tobacco smoke, discourage the use of tobacco and impose progressive restrictions and take concerted action to eventually eliminate all direct and indirect advertising, promotion and sponsorship concerning tobacco

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