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Thymosin beta-4: actin sequestration, progenitor differentiation, and neurite growth Thymosin beta-4s mechanism starts from a completely different place: it is the principal intracellular G-actinsequestering peptide, binding monomeric actin and holding it in a polymerization-incompetent pool until the cell needs it a fundamental role in cytoskeletal dynamics, cell migration, and shape change
doi: 10.1136/gutjnl-2021-325428
Standard TB-500 protocol: Loading phase (Weeks 1-4): 5mg twice weekly (Monday/Thursday) Total per week: 10mg Total for loading: 40mg (8 vials of 5mg) Maintenance phase (Weeks 5-12): 2-5mg once weekly Total per week: 2-5mg Total for maintenance: 16-40mg (3-8 vials) Example: 5mg vial + 2ml water = 2,500mcg/ml 5mg dose (5,000mcg) = draw 2.0ml (full vial) 2.5mg dose = draw 1.0ml TB-500 doses are MUCH larger than BPC-157
IBP1 AA Sequence GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA Predicted Molecular Mass 9.1 kDa Molecular Weight Approximately 11 kDa, based on SDS-PAGE under reducing conditions
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