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View Study [5]"Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris" Lu Z, Liu N, et al., 2023 Finding: Purified LR3 IGF-1 displayed excellent bioactivity for cell proliferation comparable to standard IGF-1, confirming that the molecular modifications preserve its biological function while extending its active lifespan

408 Studies have shown that the loss of GLP-1R in astrocytes can impair mitochondrial integrity, leading to the dysfunction and inhibition of glucose uptake and -oxidation