Technology Roadmap 3.6
Introduction The technology of semen cryopreservation effectively promotes the application of technologies including genetic resource conservation, zootechnical management, and artificial insemination ( However, the cold shock and alterations in atmospheric oxygen seriously led to biochemical, biophysical, ultrastructural, molecular, and functional alterations ( To ameliorate oxidative stress-related damage, the supplementations of antioxidants, including vitamins, coenzymes, exosomes, liposomes, nanomaterials and trace elements such as selenium (Se), copper, and zinc to semen extender have been widely conducted ( According to a previous study, the co-supplementation of vitamin E effectively ameliorates the low toxicity threshold of Se ( GSH, an endogenous antioxidant synthesized from different amino acids including glycine, cysteine, and glutamate, effectively inhibits oxidative stress-related damage and altered ROS production level ( in vitro development
While natural presence in the body is reassuring, supplementation introduces higher concentrations than the body typically manages, which can occasionally lead to side effects, particularly in vulnerable populations or when combined with certain medications
J Sci Food Agr 19(15):16341641
