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Minor canker sores Minor canker sores are the most common and: Are usually small Are oval shaped with a red edge Heal without scarring in one to two weeks Major canker sores Major canker sores are less common and: Are larger and deeper than minor canker sores Are usually round with defined borders, but may have irregular edges when very large Can be extremely painful May take up to six weeks to heal and can leave extensive scarring Herpetiform canker sores Herpetiform canker sores are uncommon and usually develop later in life, but they're not caused by herpes virus infection

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These patients had experienced very high long-term environmental exposure to cadmium from contaminated rice