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Epigenetics is usually defined as heritable alterations in gene expression patterns that are not directly caused by modifications encoded in the nucleotide genome sequence but are caused by posttranslational modifications in DNA and histone proteins and by the regulation of non-coding RNAs (ncRNAs) [6]

But a growing number of Israelis have started smoking loose tobacco, which costs about 43 percent less than buying the same amount of tobacco in a pack, according to Israeli daily Haaretz

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