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Quantifying ROS levels using CM-H2DCFDA and HyPer
This process resulted in increased subchondral bone stiffness, which subsequently altered the local biomechanical environment of the joint, exacerbating cartilage damage and accelerating the progression of OA (Sowers et al., 1996
10.3389/fnins.2024.1477519 Front
Sci Transl Med 7(270):270276 Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, ORegan D, Ware JS, Hubner N, Cook SA (2017) Titin-truncating variants affect heart function in disease cohorts and the general population
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