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Common side effects may include pain or redness at the injection site, mild diarrhea, or headaches [3]

Tell your prescribing doctor if you have any of these conditions, which can increase B12 shot side effects: An allergy to cobalt Kidney disease Severe megaloblastic anemia Side Effects from B12 Shots The most common B12 shot side effect is swelling at the injection site

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Patients have reported feeling more vibrant and noticing an acceleration in their weight loss when these injections are part of a medically supervised plan