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Collectively, these features may have reduced the precision of cross-arm estimates and increased the probability of type II error

Interestingly, we found that succinate accumulated only in Gclc- deficient B cells and not in Gclc- deficient effector T cells nor Tregs 43,44

References 1 FDA Wegovy (semaglutide) Prescribing InformationFDA-approved labeling for the standalone semaglutide molecule (GLP-1 receptor agonist) for chronic weight management

The mechanism, when it was finally established, was elegant: selenocysteine is encoded by the genetic code's stop codon UGA, but only in specific mRNA contexts where a particular structural feature (called the SECIS element) signals the ribosome to insert selenocysteine instead of stopping translation