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Trader sentiment reflects uncertainty around whether formal Category 1 placement occurs before or after that meeting, given the distinction between removal from Category 2 and affirmative listing, as well as ongoing questions about manufacturing standards and clinical evidence thresholds

Its a staged approach, McLaughlin said

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Numerous randomized controlled trials, many in subjects with existing hyperhomocysteinemia and vascular dysfunction, have demonstrated that supplementation with folic acid, alone or combined with vitamin B 6 and vitamin B 12 , effectively reduces fasting plasma homocysteine concentration