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Frequency varies, but most users start with 1-2 sessions per week and adjust based on results

Animals in the second group were treated with one intraperitoneal injection of polychlorinated biphenyl (Aroclor 1254) 500 mg kg -1 and were sacrificed after 7 days, while those in the third group were treated with intraperitoneal injection of 3-methylcholanthrene 20 mg -1 kg -1 day -1 for two days and were sacrificed 48 hours after treatment

[1] For those on oral therapy, a repeat B12 level may be checked after several months to confirm response

US patent 0337024, Allison Coffin, Joseph Harding, Leen Kawas, Phillip Uribe, "Novel Lead Compound for Otoprotection: Targeting HGF Signaling with Dihexa", issued 2015-11-26 "Dihexa" (PDF)