Sermorelin: Mimics natural GHRH, stimulating GH release
TABLE 3 Thyromimetic compounds in clinical trials To date, 4 different compounds have been employed in clinical trials, originally studied for their ability to reduce LDL cholesterol, in particular sobetirome and eprotirome, however, in recent years, TR agonists have been considered for NAFLD/NASH treatment in particular, MB07344/VK2809, and resmetirom
doi: 10.1053/j.gastro.2019.11.312 4 CohenJCHortonJDHobbsHH
BPC-157: The Angiogenic Healer BPC-157's healing effects center on blood vessel formation and cytoprotection: VEGF Upregulation: Increases vascular endothelial growth factor, promoting new blood vessel formation to injured tissues (PMID: 27847966, PMID: 40789979) Nitric Oxide System: Modulates NO pathways, protecting tissues from oxidative damage and improving blood flow (PMID: 31158953) Growth Factor Pathways: Interacts with and functionally engages growth-factordependent cytoprotective and regenerative pathways, producing growth-factorlike effects (PMID: 11718984, PMID: 40789979) Cytoprotective: Protects cells from various toxic insults including NSAIDs, alcohol, and ischemia (PMID: 31158953) Nerve Healing: BPC-157 indirectly modulates GABAergic inhibitory control, supporting nerve regeneration (PMID: 15840402) TB-500: The Cell Migration Facilitator TB-500 is a synthetic peptide designed to mimic Thymosin -4, which is well-established in actin sequestration, cell migration, wound repair, and anti-inflammatory signaling
