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Unopened shelf life An unopened Mounjaro or Zepbound pen stored in the refrigerator at 2 to 8 degrees Celsius (36 to 46 degrees Fahrenheit) remains effective until the expiration date printed on the packaging

It should not be expected to reverse severe osteoarthritis, regrow advanced cartilage loss, correct major joint deformity, heal a complete tendon rupture without appropriate orthopedic management, or replace surgery when surgery is clearly indicated

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