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Several of the clinical trials showing a skin-brightening effect included vitamin C alongside glutathione rather than testing glutathione entirely alone

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On the other hand, APAP-exposure increases neither caspase-3 nor cleaved-caspase-3 expression which was consistent with previous research that caspase-3 might not play an effect in the APAP-induced liver injury 30 (Figure 5A and 5B)