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PLoS One 8:e66830 Mattiazzi M, Vijayvergiya C, Gajewski C, DeVivo D, Lenaz G, Wiedmann M, Manfredi G (2004) The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

Combining it with another biologically active peptide such as GHK-Cu introduces additional variables that have not been studied

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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses