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discovered that simvastatin increased the expression of SREBP2 in the intestinal tract of mice and indicated that enterocyte SREBP2 overexpression was related to the expression of cholesterol excretion genes (129)

SS-31 (elamipretide) is a mitochondria-targeted peptide that has actually been studied in human clinical trials for mitochondrial and cardiac conditions, with mixed results, giving it the most clinical track record of the three