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Comput Biol Med

In addition to preventing pathogen adhesion by competitive exclusion, probiotics influence the hosts immune response, contribute to the integrity of the intestinal wall barrier, and produce substances such as bacteriocins, organic acids, and metabolites that can inhibit pathobiont growth [9, 10]

In one study, the CD44 rs1467558 polymorphism was reported to be significantly associated with an ALT rise in independent cohorts of patients given a therapeutic dose of 4 g/day of paracetamol over 7 days [42]