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Although several carcinogens were already known at the time (for example, benzo[a]pyrene was isolated from coal tar and demonstrated to be a potent carcinogen in 1933), none were known to be contained in adequate quantities in tobacco smoke

A team of researchers including Roberta Freitas-Lemos, assistant professor at Virginia Techs Fralin Biomedical Research Institute at VTC, found that if menthol products were unavailable, smokers found replacement therapies such as nicotine gum and lozenges were practical alternatives, potentially improving health outcomes for people who use menthol cigarettes