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Copper ions catalyze the oxidation of Vitamin C (ascorbic acid), causing it to break down rapidly and potentially creating irritating byproducts

[14] This complex consists of the following symptoms: Impaired perception of deep touch, pressure and vibration, loss of sense of touch, very annoying and persistent paresthesias Ataxia of dorsal column type Decrease or loss of deep muscle-tendon reflexes Pathological reflexes Babinski, Rossolimo and others, also severe paresis

Kraus et al., Nature (2014), on NNMT and diet-induced obesity

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