(12)Fmoc-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- (12) Preparation of Fmoc-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-resin: (11)Fmoc-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-1050530105010603DMF3DMF2DMFFmoc-Pro-OHDIEATBTU/HOBtHBTU/HOBtBOP/HOBt105010603DMF3DMF2Fmoc-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- In the Fmoc-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-resin in step (11), add the decapping reagent and react at 1050C 5 to 30 minutes, dry with a vacuum pump, re-add the decapping reagent at 10 to 50 C for 10 to 60 minutes, dry, wash with isopropanol for 3 times, DMF for 3 times, re-distilled DMF for 2 times, add Dissolve Fmoc-Pro-OH, DIEA, TBTU/HOBt or HBTU/HOBt or BOP/HOBt mixture in DMF, react at 10-50C for 10-60 minutes, dry with vacuum pump, wash with isopropanol 3 times, DMF Washed 3 times, washed 2 times with re-distilled DMF, and dried to obtain Fmoc-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu- Val-resin
Half Life: 8 minutes
Although both have many functions, much attention has been paid to their influence as antioxidants
B12 injections can last for one month with slow release into the blood, says Dr
