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One possible mechanism which could link both vitamin B 12 and folate with depressive and psychotic disorders relates to their role in the one-carbon metabolism, which is implicated in diverse processes including DNA methylation, epigenetic control of gene expression, DNA synthesis, membrane signaling, maintenance of cellular redox homeostasis and detoxification capacity [54]

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Similarly, in skimmed milk powder stored at 37 C, folate content decreased by 13% and 30% in nitrogen and by 86% and 88% in oxygen atmosphere after 25 and 105 days, resp