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When three lines of human cancer cells (SH-SY5Y neuroblastoma, U937 histolytic cells, breast cancer cells) were incubated with 1-10 nanomolar GHK, the programmed cell death system (apoptosis) was reactivated and cell growth inhibited, suggesting the peptide can restore normal growth control mechanisms in dysregulated cells

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Structure of the glutathione (GSH)

All these have suggested that paeoniflorin might improve RA by inhibiting inflammation mediated by the ROCK/NF-B signaling pathway