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Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes

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The other authors report no relevant financial relationships which, in the context of their contributions, could be perceived as a potential conflict of interest

The effect of DSePA administration on RP was studied by subjecting mice to thoracic irradiation (X- or -rays, 18 Gy), treating them with DSePA (2.5 mg/kg body weight for three time a week for 6 months beginning on the day of irradiation) during the post-irradiation period and monitoring the incidence of RP through immunohistochemical and CT analysis (Table 2) [61, 62]