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Astrocytic atrophy following status epilepticus parallels reduced Ca 2+ activity and impaired synaptic plasticity in the rat hippocampus

BioMed Research International, 2012, 153626

This controls the depth of ablation, insuring effectiveness while limiting complications

The authors have investigated three treatments to correct metabolic abnormalities which have demonstrated improvement in behavior and/or metabolism, namely the combination of methylcobalamin (mB12) with low-dose folinic acid (LDFA) to treat oxidative stress in an open-label study (James et al., 1A demonstrates where these agents are believed to act within four major interconnected metabolic pathways that are known to be disrupted in ASD