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Alexis A, Moiin A, Waibel J, Wallace P, Cohen D, Laquer V, et al

Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells

In 2019 a multinational collaborative study of data collected in 204 countries and territories between 2000 and 2019 indicated that obesity contributed approximately 5 million deaths from major non-communicable diseases

Through sulforaphanes ability to activate the mammalian Nuclear Factor Erythroid 2-related Factor 2 (NRF2) pathway, these beneficial properties extend beyond plants