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The Chronic Pain Cycle In many cases, chronic pain management follows a predictable escalation pattern: short-term relief symptom return escalating intervention increasing side effects Over time, this cycle can contribute to nutrient depletion, impaired detoxification, hormonal disruption, immune suppression, and delayed tissue repair , making pain hardernot easierto resolve

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This connection is mainly facilitated by the vagus nerve, which regulates digestion, heart rate, and the immune system as part of the parasympathetic nervous system [13]

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