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Thus, an improved understanding of the regulation of UA and its neuroprotective action in the human brain will shed further light on neurodegenerative processes and potentially identify novel targets for pharmacotherapeutic intervention

Mol Psychiatry 2016

In recent decades, the following treatments for IC/BPS have been recommended as replenishment of the glycosaminoglycan layer to control urothelial defects, administration of amitriptyline or imipramine to inhibit neurological hyperactivity, suppression of allergies by antihistamines, and non-steroid anti-inflammatory drugs for pain control (Homma et al., 2020)

The route of administration, dosage, and injection technique all influence potential side effects