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[26] Another publication looked at cessation behaviors in the context of a tax increase on vapor products and found that 32,400 smokers in Minnesota were deterred from quitting cigarettes after the state implemented a 95 percent excise tax on vapor products.[27] The substitution effect is also evident looking at the smoking rates in the U.S
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Tobacco smoke disrupts gut microbiota homeostasis driving metabolic dysfunction and multi-organ pathologies through inflammatory-metabolic axis dysregulation Tobacco smoke exposure disrupts gut microbial homeostasis, triggering metabolic dysregulation and systemic pathologies, including weight loss, cardiovascular disease, diabetes mellitus, and hepatic dysfunction through microbiota-derived inflammatory mediators and metabolite imbalances
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