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KamiyaTOsagaSKubotaEFukudoSMotoyaSMurakamiKet alQuestionnaire-based survey on epidemiology of functional gastrointestinal disorders and current status of gastrointestinal motility testing in Asian countries

Animal studies show no toxicity up to high doses, but human reports are anecdotal

10.1186/s12958-025-01380-5 66 VillalbaJ

Research indicates Dihexa treatment can improve functional outcomes in animal models of cognitive impairment, with behavioral improvements correlating with structural brain changes including increased synaptic density and improved neural connectivity patterns