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The molecule contains a cysteine-linked disulfide bridge that constrains the peptide into a cyclic conformation, an important feature for maintaining its signaling profile in biochemical and adipocyte-based assays

The -diversity analysis (Figure S2B-F) showed that Chao1, Observed species, Faith_PD, Shannon, and Simpson indexes of the Alcohol groups were reduced than those of the Control groups at weeks 6, 8, and 10, respectively ( P 1 and P 5), and there were 231 common OTUs

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However, further studies are necessary to elucidate the mechanism by which MEP provides the presumed reactivation of dormant estrogen receptors