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The NHS hypokalaemia overview explains why it matters, and clinical references such as StatPearls on B12 deficiency treatment specifically flag monitoring potassium during the early loading phase in people who were severely deficient

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Increased oxidative stress, inflammation and lipotoxicity associated with hyperglycaemia and insulin resistance potentially impair vascular endothelial function and increase endothelial permeability, leading to the penetration of glycated and oxidized low-density lipoprotein (LDL) cholesterol into the endothelium, i.e., initiation of atherosclerosis