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A study revealed that estradiol supplementation could suppress high glucose-induced apoptosis in trophoblasts, mitigate oxidative stress, and reduce placental necrosis in mouse models of GDM [30]

Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor

405,600,601,602 These findings underscore the importance of itaconate in immune modulation and metabolic reprogramming, highlighting its potential in liver repair