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Early work in Paul Talalays lab at Johns Hopkins identified NQO1 as a key and highly responsive Phase 2 enzyme, the measurement of which has been a reliable and highly predictive indicator of the cytoprotective potential of both natural and synthetic compounds [78]

For example, sourdough-leavened breads are more digestible than conventionally made breads due to the pre-breakdown of gluten by lactic acid bacteria (LAB) through proteolysis during fermentation (37)

chinense : Lycium chinense LAK: lymphokine-activated killer LBPs: Lycium barbarum polysaccharides LWB: Lacto-Wolfberry MDD: major depressive disorder MPOD: macular pigment optical density MS: metabolic syndrome NAFLD: non-alcoholic fatty liver disease PPEE: postprandial energy expenditure RP: retinitis pigmentosa StD: subthreshold depression The authors would like to express their sincere gratitude to the School of Food Science and Environmental Health at Technological University Dublin, Grangegorman, for providing the resources and support necessary to undertake this final-year research project as part of the BSc (Hons) Pharmaceutical Healthcare programme

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