Probably, the consumption of GSH and other antioxidants in reactions of degradation of lipid peroxidation products, affects the decrease of GPx and GST enzymes activity, and as the process of cataractogenesis progresses towards mature cataract, all lens structures become affected by the changes, which probably leads to the change of enzyme molecules themselves
She explains that menopausal women often show an increase of antioxidant capacity as well as lower glutathione levels along with high levels of oxidative damage. According to Tennant, this rise in antioxidant capacity may be compensatorya protective response as the body ramps up defenses to counteract mounting oxidative stress.Since glutathione levels decrease while oxidative stress increases, its reasonable to consider supplementing with glutathione or NAC, alongside lifestyle interventions like exercise, diet, sleep, stress management, and possibly hormone replacement therapy, Tennant says
## The difference between a properly reconstituted vial and a mishandled one can mean the difference between full potency and wasted medication
Cysteine the rate-limiting amino acid for GSH synthesis is the compound NAC donates after its acetyl group is cleaved
