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The bypassing pathway may be the inferior anterior pancreaticoduodenal vein (with a reduction in duodenal congestion lesions) (Amic et al., 2018) and arcade vessels (with a reduction in left colic vein and artery occlusion-induced ischemic reperfusion colitis) (Duzel et al., 2017)

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The study found the peptide well-tolerated with minimal toxicity risk, though adverse events were described as mild to moderate