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Cagrilintide is a new drug that helps lose weight

CagriSema data from body composition scans in REDEFINE 1 showed that approximately 67% of total weight loss came from fat mass and 33% from lean soft tissue mass

It blocks NNMT , an enzyme that wastes niacin (NAM) and methyl groups, so your cells keep more NAD for mitochondrial upkeep and more SAM for healthy methylation

10.1111/rssa.12010 25.Adachi S, Kawamoto T, Otsuka M et al (2000) Enteral vitamin B 12 supplements reverse postgastrectomy B 12 deficiency [DOI] [PMC free article] [PubMed] 26.Bensky MJ, Ayalon-Dangur I, Ayalon-Dangur R et al (2019) comparison of sublingual vs