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Studies in diabetic animal models show that antioxidant treatment with N-acetyl cysteine and -tocopherol dramatically reduces oxidative stress, increases antibiotic sensitivity of biofilms, and promotes proper collagen deposition and remodeling

82 , 83 , 89 , 90 , 92 Among individuals of African ancestry who have one copy of e3 and one of e4, those with a particular variant of e3 called R145C are at increased risk of developing Alzheimer's dementia compared with those who do not have this variant

And the medications reduce food cravings, which also may be true for cravings for alcohol and other drugs