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Like the peptides themselves, however, the combinations of agents have not been well studied

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These drugs should not be used to treat painless DPN because they do not provide benefits for these patients

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RBP activates the PI3K/AKT pathway by enhancing the cross-talk between IGF1R and the HER2 receptor, which leads to drug resistance (Thomas et al., 2013)

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Examples include SCFAs like butyrate or propionate, which can be given orally or even intravenously [260]

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