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Esposito G, Dottori L, Pivetta G, et al

Innate immunity and inflammation, two faces of the same biological coin The first line of immune defense against pathogens, before adaptive immunity (antibodies, T cell responses) develops, is called innate immunity

A large amount of oxidative stress occurs in patients with type 2 diabetes, resulting in complications, and the increase in oxidants comes from mitochondria that are not functioning and NOX1 (NADPH oxidase 1) in the liver [20, 21]

Clinical strategies pair anti-inflammatory peptides with lifestyle and nutrient support to provide hormone-producing cells with the substrates and low-stress environment they require in order to resume normal output