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4.1.15 Shikonin Pengs study (Peng et al., 2022) showed that shikonin could improve cecal ligation and perforation-induced AKI and LPS-induced dysfunction of RTECs

If the rate of absorption is rapid relative to distribution (this is always true for rapid intravenous administration), the concentration of drug in plasma that results from an appropriate loading dosecalculated using the apparent volume of distributioncan initially be considerably higher than desired

All injections were performed under general anesthesia using ultrasound guidance by a trained physiatrist under sterile conditions

World J Gastroenterol (2023) 29:2078