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Research has demonstrated that BPC-157 exhibits a unique "modulatory" effect on NO pathways [5]: When NO is depleted: BPC-157 appears to upregulate nitric oxide synthase (NOS) activity and increase NO production, helping restore normal signaling

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations AAD: amino-actinomycin GSH: reduced form of glutathione GSSG: oxidized form of glutathione HR: hypoxia-reoxygenation IR: ischemia-reperfusion LV: left ventricle LVDP: left ventricular developed pressure NAC: N -acetylcysteine PE: phycoerythrin ROS: reactive oxygen species REFERENCES Baker JE 2004 Oxidative stress and adaptation of the infant heart to hypoxia and ischemia

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