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A.ZubairS.AteeqH.DabeerK.PachauriS.AjmalM.et al (2018)

At this time, the evidence that excess B12 may be harmful is limited and largely circumstantial

[1] [2] It is administered once weekly via subcutaneous injection and should be used alongside diet, physical activity and behavioural support

The Connectivity Map approach compares the gene-expression signature a compound induces in cultured cells against a reference database of signatures, inferring which pathological patterns the compound might counteract