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Dermoscopy offers an exciting non-invasive tool to confirm as well as understand the stage of disease and can guide future management as well
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Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
NAPQI Formation Highest in FIRST Trimester 43% HIGHER The same Brookhuis 2021 study found: The estimated molar dose fraction of NAPQI was the highest in the first trimester (median (IQR): 11 (9.113.4%), followed by the second (9.0 (7.511%)) and third (8.2 (6.810.1)) trimester compared with non-pregnant women (7.7 (6.49.4%)).[] **This represents a 43% INCREASE in toxic NAPQI formation in the first trimester** (11% vs 7.7%)precisely when the fetal brain is most vulnerable and undergoing critical early development
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