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Contribution of the Nrf2 Pathway on Oxidative Damage and Mitochondrial Failure in Parkinson and Alzheimers Disease

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A transient breach in the epithelial barrier leads to the resistance to colitis This study was the first direct attempt to understand how physiologic breaks in the mucosal barrier, which must occur for homeostatic regulatory T cells to develop (Figure 1), may differ from the pathological mucosal barrier defects widely implicated in promoting inflammation of the underlying lamina propria